منابع مشابه
The path to personalized medicine.
n engl j med 363;4 nejm.org july 22, 2010 301 to human illness, identified genetic variability in patients’ responses to dozens of treatments, and begun to target the molecular causes of some diseases. In addition, scientists are developing and using diagnostic tests based on genetics or other molecular mechanisms to better predict patients’ responses to targeted therapy. The challenge is to de...
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Psychiatric disorders are among the most common human illnesses; still, the molecular and cellular mechanisms underlying their complex pathophysiology remain to be fully elucidated. Over the past 10 years, our group has been investigating the molecular abnormalities in major signaling pathways involved in psychiatric disorders. Recent evidences obtained by the Instituto Nacional de Ciência e Te...
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type 2 diabetes mellitus (t2dm) is recognized as a public health problem and increasingly prevalent illness. key elements of the guideline for diabetes care are based on evidence-based medicine approach and apply for population, not individuals. however, individualized care can improve diabetes management. personalized medicine is otherwise called precision medicine tries to find better predict...
متن کاملGraduate entry to medicine: widening psychological diversity
BACKGROUND At Nottingham University more than 95% of entrants to the traditional 5-year medical course are school leavers. Since 2003 we have admitted graduate entrants (GEM) to a shortened (4-year) course to 'widen access to students from more disadvantaged backgrounds'. We have recently shown that the GEM course widens academic and socio-demographic diversity of the medical student population...
متن کاملRoadmap to personalized medicine
Standard clinical protocols and the concept "one drug fits all" that are currently used to treat illness in many cases are not effective, and strikingly so in the treatment of cancer, where 75% of therapeutic schemes are ineffective. The concept of personalized medicine is that the treatment of the disease is designed on the basis of the individual needs of each patient and the factors that inf...
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ژورنال
عنوان ژورنال: Clinical and Translational Science
سال: 2011
ISSN: 1752-8054
DOI: 10.1111/j.1752-8062.2011.00345.x